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Type II alveolar cells, a major cell type infected by SARS-CoV-2, possess unique immunologic properties and appear to play a role in improving the outcome of respiratory viral infections.
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Using a novel proteomics approach, CHOP researchers have identified a host protein that restricts herpes simplex virus 1 (HSV-1) infection.
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CHOP researchers have developed a sequencing method to detect RNA modifications that regulate RNA splicing during adenovirus infection.
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In a study published in Nature Microbiology, CHOP researchers uncover a ubiquitination mechanism that helps adenovirus replicate efficiently in host cells.
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Using a powerful new tool to massively sequence genetic code in heart cells may lead to more precise treatments for heart disease.
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A CHOP scientist advocates providing automated updates to clinical genetics tests to account for new knowledge that may benefit patients and families.
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A CHOP scientist found that RNA molecules help control how the immune system affects infection and inflammation. The research may yield new treatments for asthma, IBD and other diseases.
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The Division of Genomic Diagnostics at Children’s Hospital of Philadelphia has launched AUDIOME, a comprehensive genetic test for the diagnosis of nonsyndromic hearing loss in children (NSHL).
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CHOP’s Pathology and Laboratory Medicine Department recently received its renewed accreditation from the College of American Pathologists (CAP), based on a recent on-site inspection.
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The Division of Genomic Diagnostics at CHOP has launched a series of hereditary and somatic cancer gene panels to facilitate a precision medicine approach to cancer diagnostics.